Your October 25 NFL Sunday plan: all 12 matchups, Tucson kickoff times, updated injuries and score picks, plus a 10 AM opening at Famous Sam’s River Road.
Your Sunday game plan: every kickoff in Tucson time
Seven games at 10 AM. Arizona in the afternoon. Kansas City in Seattle under the lights. Sunday, October 25 is built for a full football day in Tucson. Famous Sam’s River Road opens at 10 AM for the morning window, with breakfast available until noon. The Cardinals are our afternoon centerpiece; Green Bay–Detroit could supply the fireworks; Seattle is our prime-time upset call.
The 10 AM lineup: 49ers at Falcons; Bengals at Ravens; Buccaneers at Panthers; Giants at Texans; Colts at Vikings; Dolphins at Jets; Browns at Titans. The afternoon: Broncos at Cardinals at 1:05 PM, then Packers at Lions and Rams at Raiders at 1:25 PM. Sunday Night Football: Chiefs at Seahawks at 5:20 PM.
Pittsburgh at New Orleans opens the day in Saint-Denis, France, at 6:30 AM, before Famous Sam’s opens. All times here are Tucson MST, three hours behind Eastern Daylight Time on October 25. Buffalo, Jacksonville, the Los Angeles Chargers and Washington are on bye. Cowboys–Eagles is Monday.
Pick your window and bring your football people to 1970 W. River Road, Tucson, AZ 85704. Call (520) 292-0492 or use the page’s Get Directions link to plan your visit. Below: the matchup details that matter, confirmed injury developments and our score prediction for every Sunday game.
6:30 AM — Steelers at Saints: find a rhythm in France
The international opener asks both teams to establish a rhythm far from their usual routine. Our read: Pittsburgh’s best route is patient offense paired with defensive disruption. Make New Orleans work through long possessions, then capitalize when a sack or penalty pushes the Saints behind schedule.
New Orleans can counter by getting the ball out quickly and making Pittsburgh defend the width of the field. Watch the first two third-down series: manageable distances would keep the Saints’ full playbook available; repeated third-and-long would allow Pittsburgh to dictate the rush. Field position and the kicking game could decide a close finish.
Our prediction: Steelers 24, Saints 20. Pittsburgh gets our narrow edge, but an efficient Saints passing day could flip it. Tucson viewing note: this 6:30 AM kickoff happens before Famous Sam’s 10 AM Sunday opening.
10 AM — 49ers at Falcons and Bengals at Ravens
49ERS AT FALCONS — San Francisco’s unbeaten record creates the headline; its injury list creates the intrigue. The 49ers have ruled out Mike Evans, Deebo Samuel Sr. and Nick Bosa. Those absences remove established receiving options and a major pass-rush threat. Our read: San Francisco must manufacture clean throws through formation, motion and timing, while Atlanta should force the visitors to tackle through sustained possessions.
Watch whether Atlanta can generate pressure without sending extra rushers. That would crowd the passing windows available to San Francisco’s remaining targets. If the 49ers get comfortable pockets, they can keep the game on schedule through shorter completions. Our prediction: 49ers 27, Falcons 24. We still lean San Francisco, with the confirmed absences making Atlanta a credible upset threat.
BENGALS AT RAVENS — Saturday update: Baltimore has ruled Lamar Jackson OUT with an ankle injury; Tyler Huntley will start. The Ravens also ruled out defensive starters Jaylinn Hawkins and Tavius Robinson in Friday’s report. Cincinnati comes off a bye with a clean final injury report. The availability gap gives the Bengals a clearer route than Friday’s uncertain quarterback picture suggested.
Our read: Cincinnati should test the replacement defenders with route combinations across the middle. Baltimore needs a controlled ground game that keeps Huntley out of third-and-long and reduces the number of Bengals possessions. A short-field turnover could still swing it. Our updated prediction: Bengals 27, Ravens 20. Jackson’s confirmed absence strengthens our Cincinnati lean.
10 AM — Buccaneers at Panthers and Giants at Texans
BUCCANEERS AT PANTHERS — Baker Mayfield is officially questionable with a right-thumb injury, although Todd Bowles has said he is expected to return. Tampa Bay has ruled out Emeka Egbuka, Luke Goedeke and Antoine Winfield Jr., so even a quarterback return leaves important holes. Carolina also has edge absences: Jaelan Phillips and Thomas Incoom are out. This is a matchup between units adapting to missing personnel.
Our key is Tampa Bay’s protection against Carolina’s pressure plan. If Mayfield plays, useful early completions would help him establish a rhythm without asking him to rescue repeated long-yardage situations. Carolina should make the Buccaneers defend full possessions and finish its best drives with touchdowns. Our prediction: Panthers 23, Buccaneers 20. An effective Mayfield return is the clearest reason this pick could be wrong.
GIANTS AT TEXANS — New York has named J.J. McCarthy its starter for the trip to Houston, with Jameis Winston backing him up. The Giants enter at 3-2-1; Houston is 2-4 after winning its past two games. The contrast is compelling: the better record belongs to the team changing quarterbacks, while the home team has the recent momentum.
Our read: Houston should change its pre-snap looks and make McCarthy confirm his answers after the snap. New York’s upset path is a balanced offense, clean special teams and a close game well into the second half. If Houston scores early and makes the Giants chase, the assignment gets harder. Our prediction: Texans 28, Giants 17. A turnover-free McCarthy performance could narrow that gap quickly.
10 AM — Colts at Vikings and Dolphins at Jets
COLTS AT VIKINGS — Indianapolis needs to solve the pressure before the snap: identify the rush, set the protection and give Daniel Jones a clear outlet. A completion that creates second-and-five is more useful than an ambitious throw that leaves another long third down. Our tactical question is whether the Colts can keep Minnesota uncertain about run or pass.
A credible ground game and play-action would slow the defense’s decisions. Falling behind would do the opposite, allowing Minnesota to attack predictable passing situations. We expect the Vikings to create enough disrupted possessions to separate, provided their offense avoids giving Indianapolis short fields. Our prediction: Vikings 27, Colts 17. Minnesota is one of our more comfortable morning leans.
DOLPHINS AT JETS — Miami arrives at 0-5 and New York at 2-4, according to the Jets’ preview. The Jets announced Adonai Mitchell will return, while Breece Hall and Dylan Parham remain questionable on Friday’s report. Their actual availability affects how many ways New York can attack. Miami should make the Jets earn patient drives instead of offering explosive gains through missed tackles.
Our read: an ordinary-looking sequence—a poor punt, a holding penalty or a failed third-and-short—could create the deciding short field. New York should resist chasing a big play on every possession; Miami needs enough rushing efficiency to keep the game from becoming a series of obvious passing downs. Our prediction: Jets 20, Dolphins 17. This belongs near the bottom of our confidence list.
10 AM — Browns at Titans: pressure versus patience
Cleveland begins a road stretch in Nashville, where quarterback Cam Ward faces the central question in the Browns’ own preview: how will Cleveland generate pressure? A pass rush can change a game without collecting a sack if it forces the quarterback to speed up his reads and miss a developing opportunity.
Tennessee’s counter should be useful first-down gains, movement and a credible ground threat. Avoiding penalties would keep Ward from repeatedly facing a third-and-long rescue attempt. For Cleveland, we’re watching whether favorable field position becomes touchdowns. In a close game, wasting a drive inside the opponent’s territory can matter more than the final yardage totals.
Our prediction: Browns 20, Titans 16. Cleveland gets the edge for the disruption we expect its defense to create. Tennessee can overturn that forecast through ball security, a controlled pace and better red-zone finishing.
1:05 PM — Broncos at Cardinals: Arizona’s spotlight
The Cardinals’ injury report puts the line-of-scrimmage battle at the center of Tucson’s afternoon game. Right guard Jon Gaines II and defensive lineman Walter Nolen III are out, and Arizona says Hayden Conner will take over at right guard. Running back Jeremiyah Love and safety Andrew Wingard are also out. Arizona must protect its pocket and maintain its run defense while adjusting to those absences.
Denver has vulnerabilities of its own. Safety Talanoa Hufanga and edge rusher Jonah Elliss are out; cornerback Pat Surtain II and running back Jonah Coleman are questionable. Arizona lists Budda Baker, Max Melton and Darius Robinson as questionable. Practicing or entering a return window does not automatically establish that a player will be active.
Our read for Arizona: get useful gains on first down, move the launch point when practical and test the coverage matchups Denver actually fields. For the Broncos: make Arizona sustain that plan, then pressure the replacement personnel on predictable passing downs. The first-half red-zone possessions are our tell. The Cardinals need touchdowns from their best drives, not a series of field goals that leaves Denver comfortable.
Our prediction: Broncos 27, Cardinals 23. Denver gets the edge because Arizona’s confirmed absences make both trenches harder to manage. The Cardinals can turn it into a home upset through efficient early downs, clean protection calls and a turnover-free afternoon. Kickoff is 1:05 PM Tucson time.
1:25 PM — Packers at Lions and Rams at Raiders
PACKERS AT LIONS — Green Bay has ruled out linebacker Zaire Franklin with a shin injury, and Edgerrin Cooper is already out for the season. Those absences turn our attention to the replacement linebackers against Detroit’s run action and throws into the middle. Detroit should make them process multiple threats rather than allow them to settle into a comfortable assignment.
Green Bay’s answer is disciplined spacing, sound tackling and enough offensive balance to keep Detroit from sitting on longer-developing routes. Watch whether the Packers can earn explosive plays without surrendering them through coverage mistakes. Our prediction: Lions 31, Packers 28. This is our pick for afternoon entertainment, with Detroit’s matchup against Green Bay’s depleted linebacker group providing the slight edge.
RAMS AT RAIDERS — Puka Nacua and Trent McDuffie are questionable; Nate Landman is out on the Rams’ final report. Those are three separate stress points: receiving production, coverage and the middle of the defense. The Raiders list Mike Washington Jr. as questionable. Los Angeles is our most injury-sensitive favorite because the lineup could materially change how it sustains drives.
If Nacua plays effectively, the Rams have a more convincing route to favorable red-zone matchups. If he cannot, Los Angeles needs a broader spread of targets and a run game that keeps the defense honest. Las Vegas should force the Rams to prove which version of the offense is available, then make replacement defenders tackle through full possessions. Our prediction: Rams 27, Raiders 21, with game-day availability capable of forcing a reassessment.
5:20 PM — Chiefs at Seahawks: our prime-time upset call
Prime time brings the day’s sharpest tension: Kansas City’s offense against a Seattle crowd that can make every protection call harder. The Chiefs are without right tackle Jaylon Moore and receiver Rashee Rice, and left tackle Josh Simmons has been placed on injured reserve. Communication and protection structure become central to the matchup.
Seattle has problems too. Zach Charbonnet, Drake Thomas and Chazz Surratt are out, while Nick Emmanwori, DeMarcus Lawrence and Uchenna Nwosu are among the questionable players on Friday’s report. The Seahawks cannot simply assume defensive depth will win the night; they need timely pressure without exposing the coverage behind it.
Our read: Kansas City should use early-down efficiency to quiet the stadium and keep Patrick Mahomes out of repeated obvious passing situations. Seattle needs sustained offensive possessions so its defense can reset. Watch the first series after halftime: if Seattle is still getting pressure and the Chiefs have not solved their communication problems, the home side has a real opening.
Our prediction: Seahawks 27, Chiefs 24. This is an upset call with low confidence, built on home-field pressure against a reshuffled Chiefs protection unit. Mahomes is the clearest reason to doubt it. Kickoff is 5:20 PM Tucson time—the evening anchor after the 10 AM and afternoon windows.
Visit Famous Sam’s: quick answers and source notes
Make your plan around the game you care about most: morning kickoffs at 10 AM, breakfast until noon, the Cardinals at 1:05 PM or Sunday Night Football at 5:20 PM. Famous Sam’s River Road is at 1970 W. River Road, Tucson, AZ 85704. Call (520) 292-0492, use Get Directions and check the official food menu before heading over.
Have a must-watch team in the crowded morning window? Call ahead to check broadcast and screen availability. Seating is first come, first served, so arriving early is the practical play. Every projected score above is an editorial prediction written before the games; matchup reads are our analysis, not reported results.
Schedule sources: NFL.com’s official 2026 Week 7 schedule, cross-checked with Tom’s Guide’s Week 7 listing. Key injury sources: Arizona Cardinals and Denver Broncos reports dated October 23; Seattle’s October 23 Chiefs–Seahawks report; and Baltimore’s October 24 announcement, “Lamar Jackson Ruled Out vs. Bengals.”
Additional facts were checked against the official 49ers, Buccaneers, Giants, Jets, Packers, Rams, Raiders and Browns matchup-week reports. Reviewed October 24, 2026. Confirmed outs are separated from questionable designations. Sunday inactive lists are normally announced about 90 minutes before kickoff; late roster changes may affect our picks.